However there’s much less of a risk of this occurring with surgical procedure than with a few of the different therapies for epididymal cysts. A examine of four,508 ultrasounds of the scrotum in male youngsters found epididymal cysts in 109 cases that did not contain a historical past of tumors, cystic fibrosis, or other causes. Practically half (47%) had been present in kids ages 2 or younger, and 14% have been then identified in males between ages 2 and 10. The testicular appendage lies between the testicle and the epididymis, while the epididymal appendage sometimes tasks from the epididymis. The testicular ache could be delicate, moderate, or severe, and only in a single testicle. A tubular construction containing blood vessels, nerves, lymphatic vessels, and the vas deferens known as the spermatic cord courses from the stomach and is connected to each testicle. Apart from containing important buildings for every testicle, the spermatic cord additionally suspends the testicles within the scrotum. Testicle pain is ache that happens in or round one or each testicles. Typically the pain starts some place else within the groin or stomach space and is felt in a single or each testicles. For gentle testicle pain, you presumably can take an over-the-counter ache reliever such as aspirin, ibuprofen, or acetaminophen. The scrotum will turn into tender because of the dead testes, and it additionally causes redness and swelling of the scrotum. It is advised that any kind of pain within the testes ought to never be uncared for and the person ought to seek medical help immediately to keep away from any complication. As compared to the left testicle, the right testicle is less susceptible to many ailments. If someone complains of sharp stabbing ache within the testicle then principally the reason behind it is the situation known as "Testicular Torsion". As talked about earlier, testicular torsion is brought on due to the twisting of the spermatic wire within the testicle. The twisting results in the chopping off of the blood provide to the testicle. If no other therapy works to treat it, a surgeon may remove it. A surgeon can repair an inguinal hernia by pushing your intestines back into your belly space and stitching the opening closed. If you are pondering of getting a vasectomy, don't stress or sweat it. Finally, decrease again pain may be treated by quite so much of different methods, including treatment, physical therapy, and massage therapy. Communicate to your physician if you are experiencing frequent decrease back pain, as it might be an indication of a more serious situation. Your doctor can diagnose the underlying explanation for your ache and recommend the most effective remedy choices for you. By being proactive and taking steps to reduce your danger of developing decrease back ache. You can reduce your danger of developing this debilitating situation, permitting you to reside a pain-free life. Getting checked out by a doctor is the best way to verify that nervousness is at the root of your testicular pain and determine wholesome ways to handle it. Some testicular conditions do not cause ache or different noticeable signs but may still have an effect on your fertility. If you and your partner are having problem conceiving, seek the advice of a health care provider for further checks. In the case of testicular cancer, a lump is fashioned on the entrance or the facet of the testicle. The clinical presentation of testicular cancer reports that the testicle can be felt firmer than regular and it could also really feel onerous or inflexible as compared to a normal one. Sometimes because of any nerve injury or nerve compression, an individual might encounter extreme ache within the decrease back and the leg and testicle. Testicles are at risk of injury; more particularly the left testicle is extra susceptible to injury because it hangs decrease than the right testicle. The harm might be as a end result of multiple reasons like accidents, fights, sports, and so forth. Depending upon the extent of the damage, treatment might vary from case to case. People who complain about ache within the testicle and leg usually misunderstood delicate pain with severe problems. Prognosis may contain a physical examination, ultrasound, urine and blood tests, and typically extra specialised checks like MRI or CT scans. Incorporating these prevention methods into day by day life not solely reduces the chance of testicular ache but also contributes to total reproductive and general health. Keep In Mind, proactive measures and regular well being check-ups are essential in sustaining long-term well-being. Testicle pain can come from infection, injury, blocked fluids, or another well being condition.
posted by Sabrina 2025-05-22 12:59:04.594102
Low testosterone is a disorder the place the testicles don't produce enough testosterone. Signs of low testosterone are erectile dysfunction, gynecomastia, lack of bone mass, decrease in body hair, decrease in muscle mass, and infertility. In sufferers with major hypogonadism, history would possibly reveal the trigger for primary testicular failure, similar to familial autoimmune disease, bodily trauma to the testes, or trauma to the testes caused by radiation, chemotherapy, or infection. If you might be experiencing signs of low testosterone such as low intercourse drive, erectile dysfunction, hair loss, and fatigue, communicate to your healthcare supplier. It is essential for all males considering testosterone alternative remedy to talk to their healthcare suppliers and bear prostate screening earlier than beginning this remedy. The conventional perception that testosterone alternative remedy is contraindicated in the presence of superior prostate most cancers is supported by sturdy evidence, 25 thus meriting a powerful recommendation against its use (Box 2). Conversely, considerations about testosterone supplementation promoting the event and growth of prostate cancer and benign hyperplasia have long been primarily based on extrapolations extra so than on actual proof or verification. After confirmation of the diagnosis, exclusion of any revers?ible causes, or contraindications to the usage of testosterone, replacement remedy could also be supplied. Methods of alternative embody injectable tes?tosterone esters, transdermal tes?tosterone (gels or patches), or oral testosterone within the form of testosterone undecanoate. In some cases, docs might select to refer sufferers to a specialty clinic for testosterone injections. So males with low testosterone, particularly those that are older, have decrease bone quantity and are more susceptible to bone fractures. This section collects any knowledge citations, information availability statements, or supplementary materials included in this article. The ICMJE is small group of editors of basic medical journals who first met informally in Vancouver, British Columbia, in 1978 to ascertain tips for the format of manuscripts submitted to their journals. Its necessities for manuscripts, together with codecs for bibliographic references developed by the united states National Library of Medication (NLM), were first revealed in 1979. Correct documentation and adherence to coding pointers are essential concerns for correct billing and affected person care management. By understanding the signs, associated codes, and best practices, healthcare suppliers can guarantee accurate and efficient coding for this condition. Hypogonadism and low testosterone 10 levels can considerably impression an individual’s well-being. Through the usage of ICD 10 codes, healthcare professionals can accurately diagnose and classify these situations. The 2012 guideline is essentially in agreement with the suggestions in our guideline, but it doesn't include newer publications. Furthermore, it was revealed at a time when extremely controversial views on testosterone and cardiovascular health had not but acquired such heightened consideration and earlier than the brand new ideas on testosterone and prostate carcinogenesis were widely publicized. Also, it was meant for a selected viewers of European genitourinary surgeons and is not simply accessible to most Canadian well being professionals. The Canadian Men’s Well Being Foundation is growing a communications plan for the rule among its public campaigns to increase awareness of testosterone deficiency points related to men’s health. These two retrospective studies recommend that testosterone would possibly induce urinary stones. Nonetheless, these results are limited as a end result of the info are derived from military service members and individuals with pathological circumstances such as prostate cancer. Therefore, these retrospective outcomes would possibly lack some extent of generalizability beyond former service members and patients with prostate most cancers. Isolated deficiency of the pituitary causes testicular hypogonadism, which might trigger low libido, erectile dysfunction, infertility, fatigue, and changes in temper. Treatment for this situation typically includes hormone alternative therapy to complement testosterone levels and handle the underlying pituitary hormone deficiency. In summary, testicular hypofunction, classified beneath ICD-10 code E29.1, represents a big medical situation characterized by inadequate testosterone production due to impaired testicular function. This situation can result in a variety of scientific implications, together with infertility, decreased libido, and various metabolic problems, which can profoundly have an result on a patient’s high quality of life. If indicators of puberty usually are not evident in boys by 14 years of age, a workup for delayed puberty is warranted. While low testosterone is extra frequent in older males, it can happen in youthful males as properly. The sections of the rule of thumb were presented to the duty pressure as an entire for evaluation and feedback at an preliminary all-day assembly; they have been circulated after the assembly for additional comments. The feedback had been collated and, along with the recommendations and evidence for the suggestions, had been introduced at a second all-day assembly for additional review and comments. An unbiased medical writer who participated at the conferences was employed to attain uniformity within the preliminary drafts of the documents. Although controlled scientific studies are wanted to confirm this method, there's growing evidence that DHEA might play an essential position within the remedy of male sexual dysfunction. To higher determine the consequences of testosterone therapy on cardiovascular outcomes among users, the FDA is requiring companies that manufacture these products to conduct a controlled medical trial. We consider the health of American males will be properly served by the presence of correct drug labels and dependable data to tell clinical decision making.
posted by Bret 2025-05-22 07:29:16.056641
When eating a diet that creates a caloric surplus, it means a man will start to gain weight ? or continue to come nearer to a state of obesity. As most individuals adhere to a Western food plan, a overwhelming majority of their meals is closely processed and refined. This combo additionally leads to problems with sexual desire and erectile dysfunction ? common symptoms amongst drinkers. Estrone, a steroid hormone found in both animals and humans, is responsible for many bodily capabilities. It works equally to estrogen at low doses however can block or restrict its ability to accumulate in the blood at high doses. There is a few evidence that excessive estrogen publicity can result in most cancers. It has been instructed that eating beans, cereals, or flaxseeds, which comprise excessive ranges of plant estrogens, might increase the risk of breast cancer. Most infants who lack entry to cow’s milk are protected to devour soy milk in its place. Soy, along with weight reduction, arthritis, mind function, and menopause, has been studied. This is an open-access article distributed underneath the phrases of the Artistic Commons Attribution License (CC BY). No use, distribution or copy is permitted which does not comply with these phrases. The National Oceanic and Atmospheric Administration regulates wild-catch fishing and sets standards that protect marine environments and fish populations [46]. U.S. fish farms present safer options because domestic rules prohibit growth hormone use [46]. Shoppers should look for certifications that guarantee fish have been raised with out hormones, antibiotics, or synthetic pesticides [8]. Lignans, that are the kind of phytoestrogens in flaxseed, can change estrogen metabolism. In postmenopausal girls, lignans could cause the body to produce less lively types of estrogen. One cup of soybeans cooked will provide you with round 22g protein, which is about the same quantity as one tuna filet. Even when men consumed greater than 75 mg of isoflavones per day (which is a reasonably high amount), testosterone didn’t budge?. There isn't any definitive answer to this query because the analysis on the matter is inconclusive. Some research counsel that tofu might impact male hormones, while different research aren't able to verify this. It is feasible that tofu could have some effect on hormones, however the extent of this effect is unknown. The concern comes principally from animal research or extreme cases of people consuming huge quantities of soy. But when researchers checked out men eating regular quantities of soy, the story is very different. Studies have suggested that isoflavones, that are compounds present in soy, corresponding to edamame, could assist to reduce the C-reactive protein levels (and thereby cut back inflammation). The finest foods to lower high estrogen levels are fibre, cruciferous greens, broccoli sprouts, green tea and probiotic-rich meals like sauerkraut. Might cut back menopause symptoms Since soy acts as a natural estrogen, it might help cut back these symptoms. In a review of 35 studies, soy isoflavone dietary supplements raised estradiol (estrogen) ranges in postmenopausal girls by 14% ( 14 ). Regardless Of a rising physique of evidence that supports the well being advantages of soybeans, some consider that males ought to keep away from consuming them if they're high in isoflavones or phytoestrogens. Soy incorporates phytoestrogens that mimic the female hormone estrogen, so some consultants advise men to not devour it. Soy, which contains isoflavones, converts them to phytoestrogens, that are just like human estrogen in both women and men. On the opposite hand, fermented dairy merchandise like yogurt and kefir are often thought-about beneficial as a outcome of their probiotic content material. These can improve gut well being, which in flip can positively affect hormone levels. Balancing dairy consumption and focusing on high quality may help keep optimum testosterone ranges. It just isn't necessary to keep away from all dairy merchandise for hormonal well being, however moderation is vital. Some studies recommend that sure dairy merchandise comprise hormones which will disrupt testosterone levels, notably these produced in high-concentration environments. As a end result, the rise in estrogen does not decrease testosterone levels or result in low sperm count. Soy consumption has been shown to benefit health, notably bone density and prostate cancer threat. Furthermore, soy reduces physique fats in males, making it easier for them to build muscle. There is a few concern in regards to the effect of phytoestrogens on estrogen ranges, but there is not any evidence that this can have a adverse influence on testosterone levels. When girls with PCOS consumed nuts greater in PUFAs, their plasma lipids and serum androgens decreased. Five giant surveys of food allergy prevalence within the US or Canada based on parent- or self-reported data, which likely overestimates prevalence, have been published over the past decade (498, 499, 513?515). These surveys highlight the variation in prevalence that exists among the many major allergens. Among adults, soy allergy prevalence was reported to be 0.1, 0.16, zero.35 and zero.6%, which, in each case, made it the bottom prevalence of any of the most important allergens. Among children and adolescents, these values have been 0.25, zero.32 and 0.5%, which as in the case of adults, made soy the bottom prevalence. In Japan, seven food allergens, of which soy just isn't one, require necessary labeling whereas in Europe, 14 meals, considered one of which is soy, require labeling (511). Estimates are that greater than 9 million People have gout and greater than 32 million have hyperuricemia (436).
posted by Marion 2025-05-22 06:36:45.928802
Some employers impose a zero-tolerance policy concerning medication, and will dismiss an employee who fails a check. Some of the highest testosterone boosters include fenugreek seed extract, which has been shown to boost both testosterone and libido. Most commonly, Efficiency Enhancing Medication (PIEDs) embody stimulants like cocaine and amphetamines as nicely as narcotics like morphine. If you are contemplating taking a testosterone booster and are concerned about the potential of failing a drug check, it's essential to grasp the potential dangers and implications. I have performed a quantity of surveys, analyses, and in-depth analysis to put these claims to the take a look at and determine if utilizing testosterone boosters will trigger you to fail a drug check. Restoration Ranger is a net site that offers direction and assist for these seeking to beat habit and obtain lasting sobriety. Our team of specialists helps individuals navigate the restoration course of and keep motivated. So, since steroids are picked up on a drug check, does this mean that testosterone boosters also take a look at positive? Anabolic steroids are artificial types of testosterone introduced into the body to restore low levels of the hormone. This prescription-only drug mimics the effects of natural testosterone and comes with high-risk components and unwanted effects. To particularly detect testosterone or other artificial androgens within the body, a specialised take a look at would be necessary. This kind of test would not usually be included in a normal drug screening. These specialised tests are extra commonly used in athletic competitions, the place using synthetic testosterone is prohibited. The term "testosterone boosters" normally refers to oral over-the-counter dietary supplements. It is essential to note that drug exams can also detect the presence of other substances, such as alcohol and certain medicines. Moreover, some drug checks may embrace screening for particular metabolites or by-products of drug use, quite than the medicine themselves. However, a couple of tweaks within the testing process enable urine tests to pick up anabolic steroids and similar substances as well. The guidelines had been released at the finish of October and go into effect on January 1, 2020. Athletes blood dope by either utilizing blood transfusions or particular medicine to increase their pink blood cell depend (haemoglobin). When they transfuse blood into their bodies, they will re-infuse their own blood (autologous) or use blood from another one that serves as a donor (homologous). When receiving a cypionate testosterone injection, you see results inside 2 days. After around 12 days, the results stage off and persist within the system for upwards of 21 days. They conduct random computerized urine testing and anabolic steroids are tested for along with the normal illicit medicine coke weed. Testosterone gel and enanthate are anabolic steroids .im using take a look at gel and enanthate for low t . In urine checks are they on the lookout for the metabolites of the medication like steroids coke amphetamines. How does the check detect the tesosterone within the urine since males produce testosterone naturally. Im taking tesosterone enanthate on my own to leap begin the low testosterone level . How would that a lot testosterone reflect on a urine take a look at for anabolic steroids. As a outcome, except you have signs caused by marijuana use, your doctor likely won’t check for it. Exams for hashish use usually look for a THC metabolite in your system. A regular blood check ordered by your doctor is unlikely to verify for drug use until they suppose your symptoms match these attributable to a particular drug. Testosterone therapy has the potential to trigger a variety of adverse events, which is why it is categorised as a Schedule III controlled substance. We understand that purchasing prompt outcome exams at a local department retailer or pharmacy would be more cost-effective for you. And, there’s certainly nothing mistaken with wanting to avoid wasting a dollar wherever you can! Nevertheless, we need to make positive you perceive that prompt outcome checks aren’t admissible in court. While it’s not a difficult steroid to find and purchase, you’ll desire a good supplier because we won’t have the advantage of top-quality pharmaceutical grade with this ester. Completely Different manufacturers can also use different carrier oils, so concentrate when you have a specific choice; this can also affect the pricing. You can achieve muscle and burn fat equally to a testosterone cycle if you’re dedicated to endeavor the type of diet and coaching routine you want to assist that muscle development. This makes Testo-Max a super replacement in your dangerous Testosterone Propionate. Testosterone Propionate is an estrogenic steroid that can convert to estrogen via aromatization. This may cause a few of the most dreaded steroid side effects, however they can be more manageable with Testosterone Propionate than they're with another types of steroids. All of the acquainted testosterone side effects can be expected with Testosterone Propionate. Nevertheless, using testosterone as a performance-enhancing drug is strictly regulated in sports activities as a outcome of its potential to offer unfair advantages to athletes. The lab exams urine samples for over 250 prohibited substances, corresponding to anabolic steroids and development hormones. It is essential to note that drug testing authorities continually replace their methods and techniques to stay one step ahead of those trying to cheat the system. As a outcome, new testing methods could also be developed sooner or later to differentiate between pure and injected testosterone. These strategies could embrace the evaluation of further markers or using extra superior analytical methods. It is important to note that the detection window for injected testosterone can differ relying on several elements, including the dosage, frequency of use, and individual metabolism. For example, opioids make the DOT record of banned medications, yet they're usually prescribed to treat average or severe pain, similar to that experienced after an accident or harm. Cocaine use could cause paranoia, headaches, impaired memory, and sensitivity to light and sounds. It also can increase the danger of heart attack, seizure, and different coronary ailments. Opioids are used for pain relief and fentanyl, codeine, morphine, hydrocodone, hydromorphone, and others. Signs can embody instant ache when injecting, swelling, and a lump forming on the injection web site for several days afterward. Testosterone steroids are the solely option for new users, although Testosterone Propionate is likely certainly one of the more difficult ones for newbies in comparability with some other esters. How you manage estrogenic unwanted facet effects also can have an extra impact on cholesterol. When using an aromatase inhibitor to regulate water retention and gyno, there is a high potential for levels of cholesterol to be worsened. Ideally, a SERM is the better choice for controlling estrogen, even if they're rarely as effective as an AI, especially if cardiovascular health is a concern for you.
posted by Effie 2025-05-22 04:44:00.443945
Une baisse de la testostérone peut être à l’origine d’un risque accru d’ostéoporose (source). En effet, le cœur est le muscle ayant le plus de récepteurs à la testostérone de tout le corps. Un manque de testostérone aurait pour conséquence un attainable affaiblissement cardiaque. Il est important de noter que ces traitements d’épilation peuvent provoquer des réactions indésirables et comportent des risques supplémentaires. La testostérone interagit constamment avec les œstrogènes et la progestérone dans l’organisme féminin. Les œstrogènes régulent le cycle menstruel et la maturation des ovules, tandis que la progestérone prépare l’utérus à une éventuelle grossesse. Le stress chronique et le manque de sommeil peuvent entraîner une diminution de la production de cette hormone. Cette hormone joue un rôle essentiel dans la vitalité, la masse musculaire, la libido et l’humeur. Booster sa testostérone après 50 ans est possible grâce à des actions simples et naturelles. C’est le check de fe?minite?, outil de contro?le du sport de haut niveau, qui leur a appris qu’elles ne pouvaient pas continuer a? vivre normalement dans leur corps. L’intersexuation non ? prise en cost ? de?s la naissance pose proble?me a? partir du second ou? ces sportives se distinguent par leurs performances. Comple?tement de?passe?es, les fe?de?rations doivent alors trancher entre exclusion et autorisation a? participer aux grandes e?preuves fe?minines internationales. À la suite de sa victoire en 2009 aux championnats du monde d’athlétisme, les nombreux checks auxquels celle-ci a dû se soumettre révèlent un hyperandrogénisme. Exclue de toute compétition, elle conteste à son tour ce règlement auprès du TAS, qui le juge discriminatoire, mais nécessaire pour préserver l’intégrité des compétitions des femmes. Il est necessary de noter que les femmes ne produisent généralement pas autant de testostérone que les hommes. Le cœur étant un muscle, un manque de testostérone aura pour conséquence une réduction de ce muscle et donc un risque accru d’infarctus. La vigilance est d’autant plus de mise si les personnes connaissent déjà des troubles cardio-vasculaires (source). En effet, certaines études pointent vers une corrélation entre taux de testostérone et capacités cognitives. En outre, des avancées dans la thérapie ciblée pour le SOPK offrent de nouvelles choices prometteuses pour les femmes. Ces traitements personnalisés prennent en compte les particularités hormonales de chaque patiente, permettant ainsi une approche plus efficace et adaptée. L’électrolyse et la thérapie au laser sont des choices pour contrôler l’excès de pilosité. "Ces déséquilibres hormonaux peuvent parfois passer inaperçus mais ont des conséquences d'une grande portée sur la santé d'une femme", prévient le Dr Ruth Williams, endocrinologue. "Le SOPK est souvent une trigger d'infertilité principale chez les femmes, et la testostérone élevée est un coupable clé", déclare le Dr Lisa Parker, spécialiste de la fertilité. ?Les symptômes physiques peuvent être assez pénibles et entraîner souvent une stigmatisation sociale?, explique le Dr Olivia Smith, dermatologue subi dans le traitement des affections cutanées hormonales. Si vous souhaitez critiquer ou développer cet article, vous êtes invité à proposer un texte au comité de rédaction (redaction chez laviedesidees.fr). L’endocrinologue, qui pratique depuis 30 ans au Centre hospitalier de l’Université de Montréal, fait partie de ces rares spécialistes qui se penchent sur la query au Québec. D'entrée de jeu, elle met en garde contre une idée reçue voulant que l'andropause soit l'équivalent masculin de la ménopause. Actuellement, il n'y a pas de données suggérant l'utilisation de la testostérone chez la femme non ménopausée. Le diagnostic n'est pas posé si une cause physique ou une autre trigger psychologique (dont une détresse relationnelle) pourraient expliquer les symptômes. Ces symptômes doivent avoir été présents pendant ? 6 mois et causer une détresse significative chez la femme. Un autre remède naturel pour réduire la testostérone et traiter l’hirsutisme ou SOPK est la réglisse chinoise. Cependant, les niveaux de testostérone des femmes peuvent s'avérer difficiles à mesurer avec précision automotive de nombreux tests de testostérone en laboratoire ne sont tout simplement pas disponibles sur le marché. La testostérone chez les femmes est une composante vitale de leur santé globale, influençant non seulement la fertilité et la libido, mais aussi la croissance musculaire, la densité osseuse et la régulation de l’humeur. Comprendre les fonctions et les effets de cette hormone permet aux femmes d’adopter des stratégies efficaces pour maintenir des niveaux équilibrés. En intégrant une alimentation équilibrée, un exercice physique régulier, une bonne gestion du stress et des habitudes de sommeil saines, il est possible de soutenir naturellement la production de testostérone. Une approche informée et proactive peut conduire à une meilleure qualité de vie et à un bien-être amélioré pour les femmes. Bien que les niveaux de testostérone soient généralement plus faibles chez les femmes que chez les hommes, il est essentiel de maintenir un équilibre hormonal pour favoriser une vie saine et épanouie. En adoptant une alimentation équilibrée, en faisant de l’exercice régulièrement, en gérant le stress et en prenant soin de sa santé globale, les femmes peuvent optimiser leurs niveaux de testostérone de manière naturelle et bénéfique. Il engendre une réactualisation de la différenciation marquée entre ? féminité ethnicisée ? et ? féminité blanche ?. De fait, les organisations sportives internationales sont plus enclines à mettre en doute le sexe des athlètes qui défendent les couleurs de pays non occidentaux. Elles développent également une culture du soupçon à l’égard de certaines fédérations sportives nationales, accusées de taire délibérément la vérité dans le however d’obtenir des médailles et de se positionner sur la scène internationale sportive et politique. Même la easy marche peut aider à perdre des kilos en trop et peut avoir un impression positif sur votre santé en général. Une raison courante pour laquelle une femme aurait une testostérone supérieure à la normale est d’avoir une glycémie élevée. Pour les hommes de plus de 19 ans, la plage normale de testostérone est de 240 à 950 ng / dL. Vous devriez toujours consulter votre médecin avant de commencer à prendre de la testostérone ou tout autre médicament ou supplément connexe. Ils seront en mesure de vous fournir des checks et de s’assurer qu’il n’y a pas d’interactions avec d’autres médicaments que vous prenez. Natural Womanhood vous permet de connaître et d'aimer votre corps - de la connaissance du corps à la conscience de la fertilité et à la santé authentique des femmes. L'utilisation à lengthy terme de traitements comme le THS peut entraîner des risques de santé plus graves, notamment une probabilité accrue de cancer du sein, de maladies cardiaques et d'AVC.
posted by Sherman 2025-05-19 20:57:30.549232